| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HAAO |
| Specificity: |
This antibody reacts specifically with HAAO |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HAAO |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Existing as two alternatively spliced isoforms, HAAO (3-hydroxyanthranilate 3, HAAO may play a role in disorders that are associated with varying levels of QUIN expression, HAAO participates in the formation of quinolinic acid (QUIN), Utilizing Fe2+ ions as a cofactor, also known as HAO or 3-HAO, and excitotoxin, and is widely expressed in peripheral organs, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, including kidney and liver, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4, 4-dioxygenase), The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
HAAO Polyclonal Antibody |
| Other name: |
Anti-HAAO Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HAAO |
| Short name: |
Anti-HAAO (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-HAAO (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4796 |
| Gene: |
HAAO |
More about : HAAO |
| Long gene name: |
3-hydroxyanthranilate 3, 4-dioxygenase |
| Locus: |
2p21 |
| Discovery year: |
1999-12-14 |
| GenBank acession: |
Z29481 |
| Entrez gene record: |
23498 |
| Pubmed identfication: |
7514594 |
| Havana BLAST/BLAT: |
OTTHUMG00000152348 |