| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CCR3 |
| Specificity: |
This antibody reacts specifically with CCR3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CCR-3 |
| Gene ID: |
1232 |
| Swiss Prot: |
P51677 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative coreceptor with CD4 for HIV-1 infection, Binds to eotaxin, MCP-3, MCP-4, RANTES and MIP-1 delta, Subsequently transduces a signal by increasing the intracellular calcium ions level, eotaxin-3, Receptor for a C-C type chemokine |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CC-CKR-3 CKR3 CD193 |
| Also known as: |
CCR3 Polyclonal Antibody |
| Other name: |
Anti-CCR3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CCR3 |
| Short name: |
Anti-CCR3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-chemokine (C-C motif) receptor 3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, C-C chemokine receptor activity, CC-CKR-3 and CD193 and CKR3 and CMKBR3, CCR3 and IDBG-30125 and ENSG00000183625 and 1232, Ccr3 and IDBG-206550 and ENSMUSG00000035448 and 12771, Plasma membranes, this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0045087 and innate immune response and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding and also this GO :0016493 : C-C chemokine receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, this GO :0016493 : C-C chemokine receptor activity, 28967 and IDBG-647811 and ENSBTAG00000001338 and 408018, chemokine (C-C motif) receptor 3 |
| Identity: |
1604 |
| Gene: |
CCR3 |
More about : CCR3 |
| Long gene name: |
C-C motif chemokine receptor 3 |
| Synonyms gene: |
CMKBR3 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 3 |
| Locus: |
3p21, 31 |
| Discovery year: |
1995-05-30 |
| GenBank acession: |
AF247361 |
| Entrez gene record: |
1232 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133484 |