| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CTNND2/delta 2 Catenin |
| Specificity: |
This antibody reacts specifically with CTNND2/delta 2 Catenin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human delta 2 Catenin |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome, Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, Beta-, Beta-catenin also complexes with the tumor suppressor protein APC, Beta-catenin associates with the cytoplasmic portion of E-cadherin, Gamma-, Gamma-catenin, Gamma-catenin interacts with presenilin 1 and is expressed in the brain, In addition, The gene encoding Gamma-catenin maps to human chromosome 5p15, Together, also known as plakoglobin, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin, is a protein that binds ?catenin and N-cadherin, such as N-cadherin and P-cadherin, the catenin/cadherin complexes play an important role mediating cellular adhesion, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling, which is necessary for the function of E-cadherin as an adhesion molecule, 2, The Alpha- |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NPRAP GT24 |
| Also known as: |
CTNND2/delta 2 Catenin Antibody |
| Other name: |
Anti-CTNND2/delta 2 Catenin |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CTNND2/delta 2 Catenin |
| Short name: |
Fluor 594, Anti-CTNND2/delta 2 Catenin |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, delta 2/delta 2 Catenin, antibody to-catenin (cadherin-associated protein) |
| Alternative to gene target: |
CTNND2 and IDBG-12568 and ENSG00000169862 and 1501, CTNND2 and IDBG-631514 and ENSBTAG00000017222 and 523661, Ctnnd2 and IDBG-132442 and ENSMUSG00000022240 and 18163, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007612 and learning and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0043005 and neuron projection and cellular component this GO :0043204 and perikaryon and cellular component this GO :0048167 and regulation of synaptic plasticity and biological process, GT24 and NPRAP, delta 2, nuclei, protein binding, this GO :0001763 and morphogenesis of a branching structure and biological process this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005912 and adherens junction and cellular component this GO :0006351 and transcription, this GO :0005488 : binding, this GO :0005488 : binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, catenin (cadherin-associated protein) |
| Identity: |
2516 |
| Gene: |
CTNND2 |
More about : CTNND2 |
| Long gene name: |
catenin delta 2 |
| Synonyms gene name: |
catenin (cadherin-associated protein), delta 2 , delta 2 (neural plakophilin-related arm-repeat protein) catenin (cadherin-associated protein) |
| Synonyms name: |
neural plakophilin-related arm-repeat protein |
| Locus: |
5p15, 2 |
| Discovery year: |
1997-06-24 |
| GenBank acession: |
U52828 |
| Entrez gene record: |
1501 |
| Pubmed identfication: |
9342840 9223106 |
| RefSeq identity: |
NM_001332 |
| Classification: |
Armadillo repeat containing |
| Havana BLAST/BLAT: |
OTTHUMG00000090511 |