| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PCYT2 |
| Specificity: |
This antibody reacts specifically with PCYT2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PCYT2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Disruption of the PCYT2 gene in mice leads to death after embryo implantation, Elevated levels of MyoD, PCYT2 (Phosphorylethanolamine transferase), PCYT2 is expressed at highest levels in heart, This product combined with diacylglycerol form phosphatidylethanolamine via the de novo Kennedy pathway, activation, also known as Ethanolamine-phosphate cytidylyltransferase, cell signaling, establishing the necessity of PCYT2 for murine development, is a 389 amino acid protein that catalyzes the formation of CDP-ethanolamine from ethanolamine, liver and skeletal muscle, phagocytosis and autophagy, reduced content of Sp1 and a changed ratio of Sp1 to Sp3 all together stimulate upregulation of PCTY2 transcription during C2C12 muscle cell differentiation, Phosphatidylethanolamine (PtdEtn) is a major membrane phospholipid which serves to play a primary role in cell membrane structure and is also involved in cell division |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ET |
| Also known as: |
PCYT2 Polyclonal Antibody |
| Other name: |
Anti-PCYT2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PCYT2 |
| Short name: |
Anti-PCYT2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PCYT2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8756 |
| Gene: |
PCYT2 |
More about : PCYT2 |
| Long gene name: |
ethanolamine , phosphate cytidylyltransferase 2 |
| Synonyms name: |
CTP:phosphoethanolamine cytidylyltransferase |
| Locus: |
17q25, 3 |
| Discovery year: |
1997-06-09 |
| GenBank acession: |
D84307 |
| Entrez gene record: |
5833 |
| Pubmed identfication: |
9083101 |
| RefSeq identity: |
NM_002861 |
| Havana BLAST/BLAT: |
OTTHUMG00000177956 |