| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
COQ10B |
| Specificity: |
This antibody reacts specifically with COQ10B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human COQ10B |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
COQ10B is a mitochondrial protein that belongs to the COQ10 family, COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects, COQ10B is elevated in hypothyroid subjects, Coenzyme Q10, However, It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, Likewise, Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases, also in subclinical conditions, both in augmented and reduced conditions, is a 247 amino acid protein encoded by the human gene COQ10B, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency, when coexistent, COQ10B |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ13448 |
| Also known as: |
COQ10B Polyclonal Antibody |
| Other name: |
Anti-COQ10B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
COQ10B |
| Short name: |
Anti-COQ10B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-COQ10B (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
25819 |
| Gene: |
COQ10B |
More about : COQ10B |
| Long gene name: |
coenzyme Q10B |
| Synonyms gene name: |
cerevisiae) , coenzyme Q10 homolog B (yeast) coenzyme Q10 homolog B (S |
| Locus: |
2q33, 1 |
| Discovery year: |
2006-01-13 |
| GenBank acession: |
AK023510 |
| Entrez gene record: |
80219 |
| RefSeq identity: |
NM_025147 |
| Havana BLAST/BLAT: |
OTTHUMG00000132745 |