| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CLSTN1/Calsyntenin 1 |
| Specificity: |
This antibody reacts specifically with CLSTN1/Calsyntenin 1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Calsyntenin 1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ALC-ALPHA, Alzheimer-related cadherin-like protein, Calsyntenin-1, Calsyntenin-1 binds synaptic Ca2+ with its cytoplasmic domain and plays a role in extracellular proteolysis, Calsyntenin-1 is also known to form a complex with X11 Beta and APP to suppress the metabolic cleavage of APP, Calsyntenin-1 may be related to the development or progression of Alzheimerâ, Expressed in brain, Golgi apparatus, KIAA0911, PIK3CD, alcalpha1, alcalpha2 or FLJ32258, also known as CSTN1, and docks vesicular cargo to KLC1, and two calsyntenin-1 isoforms are produced as a result of alternative splicing events, calsyntenin-1 is also found at lower levels in placenta, cell projections and postsynaptic cells, heart and kidney, is a 981 amino acid single-pass type I membrane protein that localizes to the membrane of endoplasmic reticulum, non-classical cadherin XB31alpha, skeletal muscle, &euro, &trade, Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses, s disease |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CSTN1 KIAA0911 CDHR12 |
| Also known as: |
CLSTN1/Calsyntenin 1 Polyclonal Antibody |
| Other name: |
Anti-CLSTN1/Calsyntenin 1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CLSTN1/Calsyntenin 1 |
| Short name: |
Anti-CLSTN1/Calsyntenin 1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-calsyntenin 1/Calsyntenin 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ALC-ALPHA and alcalpha1 and alcalpha2 and CDHR12 and CSTN1 and PIK3CD and XB31alpha, CLSTN1 and IDBG-633317 and ENSBTAG00000011823 and 514447, CLSTN1 and IDBG-88646 and ENSG00000171603 and 22883, Clstn1 and IDBG-205238 and ENSMUSG00000039953 and 65945, X11-like protein binding, nuclei, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001540 and beta-amyloid binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019894 and kinesin binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0042988 and X11-like protein binding and molecular function this GO :0042995 and cell projection and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001540 : beta-amyloid binding, this GO :0001540 : beta-amyloid binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0019894 : kinesin binding and also this GO :0042988 : X11-like protein binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0019894 : kinesin binding, this GO :0042988 : X11-like protein binding, calsyntenin 1 |
| Identity: |
17447 |
| Gene: |
CLSTN1 |
More about : CLSTN1 |
| Long gene name: |
calsyntenin 1 |
| Synonyms name: |
cadherin-related family member 12 |
| Locus: |
1p36, 22 |
| Discovery year: |
2002-05-01 |
| GenBank acession: |
AB020718 |
| Entrez gene record: |
22883 |
| Pubmed identfication: |
10048485 |
| Classification: |
Cadherin related |
| Havana BLAST/BLAT: |
OTTHUMG00000001451 |