| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
p35/CDK5P1 |
| Specificity: |
This antibody reacts specifically with p35/CDK5P1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human p35 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Although Cdk5 is expressed at the highest level in the brain of adult mice, These findings may be explained by the cloning and characterization of a Cdk5 regulatory subunit, a well-characterized regulator of cell cycle progression, brain is the only tissue from which Cdk5 can be isolated as an active kinase, designated p25, designated p35, intermediate levels in testis and low or undetectable levels in all other tissues, p35 displays a neuronal cell-specific pattern of expression, p35 is also expressed in many tissues in a truncated form, physically associates with Cdk5 and activates Cdk5 enzymatic activity, was originally isolated on the basis of its structural homology to Cdc2, Cdk5 a key regulator of cell cycle progression |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
p35/CDK5P1 Polyclonal Antibody |
| Other name: |
Anti-p35/CDK5P1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
p35/CDK5P1 |
| Short name: |
Anti-p35/CDK5P1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-p35/CDK5P1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
21261 |
| Gene: |
CDK5P1 |
More about : CDK5P1 |
| Long gene name: |
cyclin dependent kinase 5 pseudogene 1 |
| Synonyms gene: |
CDK5PS |
| Synonyms gene name: |
cyclin dependent kinase 5 pseudogene |
| Locus: |
8q24, 13 |
| Discovery year: |
2003-07-21 |
| Entrez gene record: |
392265 |
| RefSeq identity: |
NG_022432 |
| Havana BLAST/BLAT: |
OTTHUMG00000133575 |