| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Calcipressin 3 |
| Specificity: |
This antibody reacts specifically with Calcipressin 3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Calcipressin 3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Calcipressin-2, Calcipressin-3, Calcipressin-3 interacts with cardiac troponin I, Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail, RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells, is a 241 amino acid protein that potentially is involved in central nervous system development, suggesting that it may play a role in cardiac contraction events, which results in either inhibition or activation of calcineurin activity, Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DSCR1L2, Down syndrome candidate region 1 like 2, Down syndrome candidate region 1 like protein 2, Down syndrome candidate region 1-like protein 2, Down syndrome critical region gene 1 like 2, MCIP3, Myocyte enriched calcineurin interacting protein 3, Myocyte-enriched calcineurin-interacting protein 3, RCAN family member 3, RCAN3, RCAN3_HUMAN, RCN3, Regulator of calcineurin 3, hRCN3, regulator of calcineurin 3, Calcipressin-3 |
| Also known as: |
Calcipressin 3 Polyclonal Antibody |
| Other name: |
Anti-Calcipressin 3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Calcipressin 3 |
| Short name: |
Anti-Calcipressin 3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Calcipressin 3 (polyclonal) |
| Alternative technique: |
polyclonals |