| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Calcipressin 1/DSCR 1 |
| Specificity: |
This antibody reacts specifically with Calcipressin 1/DSCR 1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Calcipressin 1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
DSCR1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, DSCR1 is abundant in the brain, Human DSCR1 maps to gene locus 21q22, Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome, and skeletal muscle, heart, in particular mental retardation and/or cardiac defects, 1-q22, 2, DSCR1 protein influences cardiac and nervous system development (1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DSCR |
| Also known as: |
Calcipressin 1/DSCR 1 Antibody |
| Other name: |
Anti-Calcipressin 1/DSCR 1 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Calcipressin 1/DSCR 1 |
| Short name: |
Fluor 594, Anti-Calcipressin 1/DSCR 1 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Calcipressin 1/DSCR 1 |
| Identity: |
2708 |
| Gene: |
DCR |
More about : DCR |
| Long gene name: |
Down syndrome chromosome region |
| Locus: |
21q22, 3 |
| Discovery year: |
1990-09-10 |
| Pubmed identfication: |
1829580 |