| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NPY5R |
| Specificity: |
This antibody reacts specifically with NPY5R |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NPY5R |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A number of structurally related receptors for these peptides have been isolated, NPY-5R, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY4-R is expressed in several human tissues, NPY4-R maps to human chromosome 10q11, NPY5-R, NPY5-R localizes to the paraventricular hypothalamic nucleus, NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31, The gene which encodes NPY5-R maps to human chromosome 4q32, The human NPY5-R sequence is nearly identical to, and NPY6-R, and ileum, and other locations consistent with a role in the control of feeding behavior, and peptide YY (PYY) are related 36-amino acid hormones, but in the opposite orientation from, coronary artery, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors, including brain, isolated from rat hypothalamus, neuropeptide Y (NPY), that of the human NPY1-R sequence, the lateral hypothalamus, 2, 2, Pancreatic polypeptide (PP) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NPYR5 |
| Also known as: |
NPY5R Polyclonal Antibody |
| Other name: |
Anti-NPY5R Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NPY5R |
| Short name: |
Anti-NPY5R (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-neuropeptide Y receptor Y5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
GABAergic and biological process this GO :0042755 and eating behavior and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0060112 and generation of ovulation cycle rhythm and biological process, NPY5-R and NPYR5 and NPYY5-R, NPY5R and IDBG-43252 and ENSG00000164129 and 4889, NPY5R and IDBG-639719 and ENSBTAG00000038421 and 781872, Npy5r and IDBG-158767 and ENSMUSG00000044014 and 18168, Plasma membranes, neuropeptide Y receptor activity, this GO :0001601 and peptide YY receptor activity and molecular function this GO :0001602 and pancreatic polypeptide receptor activity and molecular function this GO :0002675 and positive regulation of acute inflammatory response and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003214 and cardiac left ventricle morphogenesis and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004983 and neuropeptide Y receptor activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0007268 and synaptic transmission and biological process this GO :0014050 and negative regulation of glutamate secretion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032229 and negative regulation of synaptic transmission, this GO :0001601 : peptide YY receptor activity, this GO :0001601 : peptide YY receptor activity and also this GO :0001602 : pancreatic polypeptide receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004983 : neuropeptide Y receptor activity, this GO :0001602 : pancreatic polypeptide receptor activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0004983 : neuropeptide Y receptor activity, 786150, neuropeptide Y receptor Y5 |
| Identity: |
7958 |
| Gene: |
NPY5R |
More about : NPY5R |
| Long gene name: |
neuropeptide Y receptor Y5 |
| Locus: |
4q32, 2 |
| Discovery year: |
1997-03-27 |
| GenBank acession: |
BC042416 |
| Entrez gene record: |
4889 |
| Pubmed identfication: |
8700207 9417917 |
| RefSeq identity: |
NM_006174 |
| Classification: |
Neuropeptide receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000161353 |