| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FADS2 |
| Specificity: |
This antibody reacts specifically with FADS2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FADS2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
C-terminal multiple membrane-spanning desaturase regions and 3 histidine box motifs, DES6, Defects in the gene encoding FADS2 are the cause of cause of fatty acid delta-6-desaturase deficiency, Expressed in adult and fetal heart and in adult liver, FADS2 (fatty acid desaturase 2), FADS2 and FADS3, FADS2 functions as a component of a lipid metabolic pathway and catalyzes the first step in the pathway, LLCDL2 or TU13, Members of this family share N-terminal cytochrome b5-like domains, Multiple isoforms of FADS2 exist due to alternative splicing events, also known as D6D, an affliction that is characterized by skin abnormalities, brain, corneal ulceration and growth failure, including FADS1, is a 444 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one cytochrome b5 heme-binding domain, lung and retina, namely the formation of unsaturated fatty acids from polyunsaturated fatty acids, regulate the desaturation of fatty acids by introducing double bonds between defined carbons of fatty acyl chains, thereby playing an essential role in the lipid metabolic pathway, Members of the fatty acid desaturase (FADS) family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FADSD6 D6D TU13 DES6 SLL0262 |
| Also known as: |
FADS2 Polyclonal Antibody |
| Other name: |
Anti-FADS2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FADS2 |
| Short name: |
Anti-FADS2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FADS2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3575 |
| Gene: |
FADS2 |
More about : FADS2 |
| Long gene name: |
fatty acid desaturase 2 |
| Synonyms gene: |
LLCDL2 |
| Synonyms name: |
delta-6-desaturase |
| Locus: |
11q12, 2 |
| Discovery year: |
1998-07-30 |
| GenBank acession: |
AF084559 |
| Entrez gene record: |
9415 |
| RefSeq identity: |
NM_004265 |
| Classification: |
Fatty acid desaturases |
| Havana BLAST/BLAT: |
OTTHUMG00000163794 |