| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SEMA6C |
| Specificity: |
This antibody reacts specifically with SEMA6C |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SEMA6C |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular â, SEMA6C, SEMA6C 2 and SEMA6C 3, The extracellular domain of SEMA6C induces growth cone collapse of dorsal root ganglion and plays a role in generation or stability of entorhino-hippocampal synapses, The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain, Three isoforms of this semaphorin exist due to alternative splicing: SEMA6C 1, also known as SEMA Y, blocks of conserved sequences and no obvious repeats, is a transmembrane protein expressed in fetal brain and adult skeletal muscle, &euro, &euro, &oelig, Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans, semaphorinâ, domain of approximately 500 amino acids containing 14-16 cysteines |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1869 |
| Also known as: |
SEMA6C Polyclonal Antibody |
| Other name: |
Anti-SEMA6C Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SEMA6C |
| Short name: |
Anti-SEMA6C (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SEMA6C (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
10740 |
| Gene: |
SEMA6C |
More about : SEMA6C |
| Long gene name: |
semaphorin 6C |
| Synonyms gene name: |
(semaphorin) 6C , and cytoplasmic domain, sema domain, transmembrane domain (TM) |
| Synonyms name: |
m-Sema Y2 |
| Locus: |
1q21, 3 |
| Discovery year: |
1999-06-25 |
| GenBank acession: |
AF339154 |
| Entrez gene record: |
10500 |
| Pubmed identfication: |
12110693 |
| RefSeq identity: |
NM_030913 |
| Classification: |
Semaphorins |
| Havana BLAST/BLAT: |
OTTHUMG00000012261 |