| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Dscam |
| Specificity: |
This antibody reacts specifically with Dscam |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Dscam |
| Gene ID: |
1826 |
| Swiss Prot: |
O60469 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Enhances netrin-induced phosphorylation of PAK1 and FYN, In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding, Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38, Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies, Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells, Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC, Cell adhesion molecule that plays a role in neuronal self-avoidance |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
M41 |
| Also known as: |
Dscam Polyclonal Antibody |
| Other name: |
Anti-Dscam Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Dscam |
| Short name: |
Anti-Dscam (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Down syndrome cellular adhesion molecule (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
40197 |
| Gene: |
DSCAM-AS1 |
More about : DSCAM-AS1 |
| Long gene name: |
DSCAM antisense RNA 1 |
| Synonyms gene name: |
DSCAM antisense RNA 1 (non-protein coding) |
| Locus: |
21q22, 2 |
| Discovery year: |
2011-05-20 |
| Entrez gene record: |
100506492 |
| Pubmed identfication: |
27666543 |
| RefSeq identity: |
NR_038896 |
| Classification: |
Long non-coding RNAs |
| Havana BLAST/BLAT: |
OTTHUMG00000086733 |