| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
STAT6 |
| Specificity: |
This antibody reacts specifically with STAT6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human STAT6 |
| Gene ID: |
6778 |
| Swiss Prot: |
P42226 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling, Carries out a dual function: signal transduction and activation of transcription |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
D12S1644 IL-4-STAT |
| Also known as: |
STAT6 Polyclonal Antibody |
| Other name: |
Anti-STAT6 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
STAT6 |
| Short name: |
Anti-STAT6 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, interleukin-4 induced (polyclonal), antibody to-signal transducer and activator on transcription 6 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
D12S1644 and IL-4-STAT and STAT6B and STAT6C, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007165 and signal transduction and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0034097 and response to cytokine and biological process this GO :0035771 and interleukin-4-mediated signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048295 and positive regulation of isotype switching to IgE isotypes and biological process this GO :0060443 and mammary gland morphogenesis and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :1902170 and cellular response to reactive nitrogen species and biological process, STAT6 and IDBG-42122 and ENSG00000166888 and 6778, STAT6 and IDBG-635695 and ENSBTAG00000006335 and 353105, Stat6 and IDBG-195602 and ENSMUSG00000002147 and 20852, interleukin-4 induced, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0002296 and T-helper 1 cell lineage commitment and biological process this GO :0002829 and negative regulation of type 2 immune response and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0019903 : protein phosphatase binding and also this GO :0042802 : identical protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0019903 : protein phosphatase binding, this GO :0042802 : identical protein binding, this GO :0043565 : sequence-specific DNA binding, signal transducer and activator of transcription 6 |
| Identity: |
11368 |
| Gene: |
STAT6 |
More about : STAT6 |
| Long gene name: |
signal transducer and activator of transcription 6 |
| Synonyms gene name: |
interleukin-4 induced , signal transducer and activator of transcription 6 |
| Locus: |
12q13 |
| Discovery year: |
1995-11-09 |
| GenBank acession: |
BC005823 BQ028928 |
| Entrez gene record: |
6778 |
| Pubmed identfication: |
9605853 8085155 |
| RefSeq identity: |
NM_003153 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000171194 |