| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TRIP13/16E1BP |
| Specificity: |
This antibody reacts specifically with TRIP13/16E1BP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TRIP13/16E1BP |
| Gene ID: |
9319 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
TRIP13 does not require the presence of thyroid hormone to interact with TR, TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing, TRIP13 is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1, The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function, Unlike most TRIP proteins which function only in the presence of hormones, Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
16E1BP |
| Also known as: |
TRIP13/16E1BP Polyclonal Antibody |
| Other name: |
Anti-TRIP13/16E1BP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TRIP13/16E1BP |
| Short name: |
Anti-TRIP13/16E1BP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TRIP13/16E1BP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12307 |
| Gene: |
TRIP13 |
More about : TRIP13 |
| Long gene name: |
thyroid hormone receptor interactor 13 |
| Synonyms name: |
thyroid receptor interacting protein 13 |
| Locus: |
5p15, 33 |
| Discovery year: |
2000-01-04 |
| GenBank acession: |
L40384 |
| Entrez gene record: |
9319 |
| Pubmed identfication: |
7776974 |
| RefSeq identity: |
NM_004237 |
| Classification: |
AAA ATPases |
| Havana BLAST/BLAT: |
OTTHUMG00000090349 |