| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NPS/Neuropeptide S |
| Specificity: |
This antibody reacts specifically with NPS/Neuropeptide S |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Neuropeptide S |
| Gene ID: |
594857 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In addition, NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites, NPS and its receptor NPSR may also play a role in asthma pathogenesis, NPS functions by binding and activating its receptor, NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP), NPSR, The N-terminal residue of NPS is always a serine regardless of the species, and increasing intracellular calcium levels thereby acting as an excitatory transmitter, arousal/anxiety responses and food intake, locomotion, Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
NPS/Neuropeptide S Polyclonal Antibody |
| Other name: |
Anti-NPS/Neuropeptide S Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NPS/Neuropeptide S |
| Short name: |
Anti-NPS/Neuropeptide S (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NPS/Neuropeptide S (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
33940 |
| Gene: |
NPS |
More about : NPS |
| Long gene name: |
neuropeptide S |
| Synonyms name: |
prepro-neuropeptide S |
| Locus: |
10q26, 2 |
| Discovery year: |
2008-01-17 |
| GenBank acession: |
BC148465 |
| Entrez gene record: |
594857 |
| Pubmed identfication: |
18181564 15312648 |
| RefSeq identity: |
NM_001030013 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000188145 |