| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Cpt1c |
| Specificity: |
This antibody reacts specifically with Cpt1c |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Cpt1c |
| Gene ID: |
126129 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Cpt1c, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine, Malonyl-CoA, Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, Unlike other Cpt1 proteins, altering subsequent feeding behaviour, an intermediate in fatty acid synthesis, and oxidation of fatty acids by, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure, mitochondria, the brain-specific carnitine O-palmitoyltransferase 1, The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ23809 CPTIC CPT1P |
| Also known as: |
Cpt1c Polyclonal Antibody |
| Other name: |
Anti-Cpt1c Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Cpt1c |
| Short name: |
Anti-Cpt1c (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cpt1c (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
18540 |
| Gene: |
CPT1C |
More about : CPT1C |
| Long gene name: |
carnitine palmitoyltransferase 1C |
| Locus: |
19q13, 33 |
| Discovery year: |
2003-11-27 |
| GenBank acession: |
AF357970 |
| Entrez gene record: |
126129 |
| Pubmed identfication: |
12376098 11001805 |
| RefSeq identity: |
NM_152359 |
| Havana BLAST/BLAT: |
OTTHUMG00000183267 |