| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SNAPIN/SNAP25BP |
| Specificity: |
This antibody reacts specifically with SNAPIN/SNAP25BP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SNAP25BP |
| Gene ID: |
23557 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing results in multiple transcript variants, As part of the SNARE complex, Biochemical studies have identified additional binding partners, Jun 2012], Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome, The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules, [provided by RefSeq, it is required for vesicle docking and fusion and regulates neurotransmitter release, The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BLOC1S7 BORCS3 |
| Also known as: |
SNAPIN/SNAP25BP Polyclonal Antibody |
| Other name: |
Anti-SNAPIN/SNAP25BP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SNAPIN/SNAP25BP |
| Short name: |
Anti-SNAPIN/SNAP25BP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SNAP-associated protein/SNAP25BP (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BLOC1S7 and BLOS7 and SNAPAP, SNAPIN and IDBG-102759 and ENSG00000143553 and 23557, SNAPIN and IDBG-632741 and ENSBTAG00000012470 and 511816, Snapin and IDBG-167545 and ENSMUSG00000001018 and 20615, nuclei, protein binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000149 and SNARE binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005730 and nucleolus and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008089 and anterograde axon car this GO transport and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0016032 and viral process and biological process this GO :0016079 and synaptic vesicle exocytosis and biological process this GO :0016188 and synaptic vesicle maturation and biological process this GO :0030054 and cell junction and cellular component this GO :0030133 and transport vesicle and cellular component this GO :0030141 and secretory granule and cellular component this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0030672 and synaptic vesicle membrane and cellular component this GO :0031083 and BLOC-1 complex and cellular component this GO :0031175 and neuron projection development and biological process this GO :0031629 and synaptic vesicle fusion to presynaptic membrane and biological process this GO :0032438 and melanosome organization and biological process this GO :0043393 and regulation of protein binding and biological process this GO :0045202 and synapse and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048489 and synaptic vesicle transport and biological process this GO :0048490 and anterograde synaptic vesicle transport and biological process this GO :0072553 and terminal button organization and biological process this GO :1902824 and positive regulation of late endosome to lysosome transport and biological process, this GO :0000149 : SNARE binding, this GO :0000149 : SNARE binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, SNAP-associated protein |
| Identity: |
17145 |
| Gene: |
SNAPIN |
More about : SNAPIN |
| Long gene name: |
SNAP associated protein |
| Synonyms gene: |
SNAPAP |
| Synonyms gene name: |
SNAP-associated protein |
| Synonyms name: |
snapin SNAP-25-binding protein biogenesis of lysosomal organelles complex-1, subunit 7 |
| Locus: |
1q21, 3 |
| Discovery year: |
2004-01-16 |
| GenBank acession: |
AF086837 |
| Entrez gene record: |
23557 |
| Pubmed identfication: |
10195194 12659861 |
| RefSeq identity: |
NM_012437 |
| Classification: |
Biogenesis of lysosomal organelles complex 1 BLOC-1 related complex |
| Havana BLAST/BLAT: |
OTTHUMG00000037086 |