| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TIRAP (isoform b) |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), WB |
| Recommended dilutions: |
ELISA (peptide) LOD: 1:128000, Western blot: 1-3ug/ml |
| Notes: |
This TIRAP antibody is specific to isoform b of the protein, <, 1, Optimal dilution of the TIRAP antibody should be determined by the researcher, p> |
| Intented use: |
This TIRAP antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
114609 |
| Purity: |
Antigen affinity |
| Description: |
Mal, Additional name(s) for this target protein: Toll-interleukin 1 receptor (TIR) domain-containing adapter protein |
| Immunogen: |
This sequence is specific for isoform b, Amino acids EGEGERDSATVSDL were used as the immunogen for this TIRAP antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the TIRAP antibody at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TIRAP (isoform b) |
| Short name: |
TIRAP Antibody (isoform b) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
toll-interleukin 1 receptor (TIR) domain containing adaptor protein (Antibody to) (isoform b) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TIRAP and IDBG-642760 and ENSBTAG00000021504 and 531079, TIRAP and IDBG-75811 and ENSG00000150455 and 114609, Tirap and IDBG-148134 and ENSMUSG00000032041 and 117149, bridging, bridging and also this GO :0035662 : Toll-like receptor 4 binding and also this GO :0035663 : Toll-like receptor 2 binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity, bridging and molecular function this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032648 and regulation of interferon-beta production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032738 and positive regulation of interleukin-15 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034137 and positive regulation of toll-like receptor 2 signaling pathway and biological process this GO :0034141 and positive regulation of toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034145 and positive regulation of toll-like receptor 4 signaling pathway and biological process this GO :0035662 and Toll-like receptor 4 binding and molecular function this GO :0035663 and Toll-like receptor 2 binding and molecular function this GO :0035665 and TIRAP-dependent toll-like receptor 4 signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0045410 and positive regulation of interleukin-6 biosynthetic process and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070935 and 3'-UTR-mediated mRNA stabilization and biological process this GO :0071221 and cellular response to bacterial lipopeptide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process this GO :0090073 and positive regulation of protein homodimerization activity and biological process this GO :2000340 and positive regulation of chemokine (C-X-C motif) ligand 1 production and biological process this GO :2000343 and positive regulation of chemokine (C-X-C motif) ligand 2 production and biological process, phosphatidylinositol-4, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005546 and phosphatidylinositol-4, this GO :0005080 : protein kinase C binding, this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0005546 : phosphatidylinositol-4, this GO :0005515 : protein binding, this GO :0005546 : phosphatidylinositol-4, this GO :0030674 : protein binding, this GO :0035662 : Toll-like receptor 4 binding, this GO :0035663 : Toll-like receptor 2 binding, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, 5-bisphosphate binding, 5-bisphosphate binding and also this GO :0030674 : protein binding, 5-bisphosphate binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030139 and endocytic vesicle and cellular component this GO :0030674 and protein binding, toll-interleukin 1 receptor (TIR) domain containing adaptor protein |
| Identity: |
17192 |
| Gene: |
TIRAP |
More about : TIRAP |
| Long gene name: |
TIR domain containing adaptor protein |
| Synonyms gene name: |
Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein |
| Synonyms: |
Mal wyatt |
| Synonyms name: |
MyD88 adapter-like |
| Locus: |
11q24, 2 |
| Discovery year: |
2003-06-05 |
| GenBank acession: |
AF378129 |
| Entrez gene record: |
114609 |
| Pubmed identfication: |
11526399 11544529 |
| RefSeq identity: |
NM_148910 |
| Classification: |
TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000140373 |