| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PCYT1A |
| Specificity: |
This antibody reacts specifically with PCYT1A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PCYT1A |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Expressed CCT A has lipid-dependent cytidylyltransferase activity (5), In cultured eukaryotic cells, The alpha isoform is located in the nucleus and is regulated by reversible phosphorylation and membrane association (3), The gene which encodes CCT A maps to human chromosome 3q (4), The rate-controlling enzyme in the phosphatidylcholine biosynthetic pathway is CTP-phosphocholine cytidylyltransferase A (CCT A) (2â, The regulation of gestational age-dependent induction of phosphatidylcholine synthesis by glucocorticoids is still unclear (1), There is significant identity between the alpha-helical membrane-binding domains of CCT A and soybean oleosin (2), this enzyme is essential for survival (3), &euro, &ldquo, 4), Increase in fetal surfactant synthesis and lung maturity is caused by the glucocorticoidal induction of enzymes required for phosphatidylcholine synthesis towards the end of gestation (1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CT CTPCT |
| Also known as: |
PCYT1A Polyclonal Antibody |
| Other name: |
Anti-PCYT1A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PCYT1A |
| Short name: |
Anti-PCYT1A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PCYT1A (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8754 |
| Gene: |
PCYT1A |
More about : PCYT1A |
| Long gene name: |
alpha , choline, phosphate cytidylyltransferase 1 |
| Synonyms gene: |
PCYT1 |
| Synonyms gene name: |
alpha isoform , choline, phosphate cytidylyltransferase 1 |
| Synonyms name: |
alpha isoform , choline, phosphate cytidylyltransferase 1 |
| Locus: |
3q29 |
| Discovery year: |
1999-05-05 |
| GenBank acession: |
L28957 |
| Entrez gene record: |
5130 |
| Pubmed identfication: |
7918629 |
| RefSeq identity: |
NM_005017 |
| Havana BLAST/BLAT: |
OTTHUMG00000155670 |