| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GBP2 |
| Specificity: |
This antibody reacts specifically with GBP2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse GBP2 |
| Gene ID: |
14469 |
| Swiss Prot: |
Q9Z0E6 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Exhibits antiviral activity against influenza virus, Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity), Hydrolyzes GTP to GMP in two consecutive cleavage reactions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GBP2 Polyclonal Antibody |
| Other name: |
Anti-GBP2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GBP2 |
| Short name: |
Anti-GBP2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, interferon-inducible (polyclonal), antibody to-guanylate binding protein 2 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
GBP2 and IDBG-100168 and ENSG00000162645 and 2634, GTP binding, interferon-inducible, nuclei, this GO :0000139 and this GO lgi membrane and cellular component this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006955 and immune response and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process, this GO :0003924 : GTPase activity, this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, guanylate binding protein 2 |
| Identity: |
4183 |
| Gene: |
GBP2 |
More about : GBP2 |
| Long gene name: |
guanylate binding protein 2 |
| Synonyms gene name: |
guanylate binding protein 2, interferon-inducible |
| Locus: |
1p22, 2 |
| Discovery year: |
1995-01-30 |
| GenBank acession: |
BC073163 |
| Entrez gene record: |
2634 |
| Pubmed identfication: |
1715024 |
| RefSeq identity: |
NM_004120 |
| Havana BLAST/BLAT: |
OTTHUMG00000010662 |