| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HSP 40-4/HDJ2/DNAJA1 |
| Specificity: |
This antibody reacts specifically with HSP 40-4/HDJ2/DNAJA1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HSP 40-4 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
HSP 40-4, Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling, The cellular redox enzyme thioredoxin interacts with HSP 40-4, The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, also known as HDJ2, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc, DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DJ2, DNAJ2, DNJA1_HUMAN, DjA1, DnaJ Hsp40 homolog, DnaJ homolog subfamily A member 1, DnaJ protein homolog 2, Dnaja1, HDJ-2, HDJ2, HSDJ, HSJ-2, HSJ2, HSPF4, Heat shock 40 kDa protein 4, Heat shock protein J2, Human DnaJ protein 2, NEDD7, Neural precursor cell expressed developmentally down regulated 7, OTTHUMP00000021193, hDJ 2, heat shock protein DNAJ like 2, member 1, subfamily A, DJ 2 |
| Also known as: |
HSP 40-4/HDJ2/DNAJA1 Polyclonal Antibody |
| Other name: |
Anti-HSP 40-4/HDJ2/DNAJA1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HSP 40-4/HDJ2/DNAJA1 |
| Short name: |
Anti-HSP 40-4/HDJ2/DNAJA1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-HSP 40-4/HDJ2/DNAJA1 (polyclonal) |
| Alternative technique: |
polyclonals |