| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RAB6A |
| Specificity: |
This antibody reacts specifically with RAB6A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RAB6A |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Accumulating data suggests an important role for Rab proteins, At least eight members of the Rab subfamily have been identified, RAB6A or RAB6A, Rab 6, Ral/Rec and Rho/Rab subfamilies, Rap, The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves, a process that appears to involve Rab protein function, also known as RAB6B, at each stage, each of which is found at a particular stage of a membrane transport pathway, either in endocytosis or in biosynthetic protein transport, exhibit 30-60% homology with Ras p21, is a 208 amino acid protein that is ubiquitously expressed and is a member of the small GTPase superfamily, is associated with secretory vesicles, the Sec4 protein, the movement of carrier vesicles, which includes the R-Ras, which is 40% homologous to Rab proteins, The Ras-related superfamily of guanine nucleotide binding proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
RAB6A Polyclonal Antibody |
| Other name: |
Anti-RAB6A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RAB6A |
| Short name: |
Anti-RAB6A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RAB6A (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9786 |
| Gene: |
RAB6A |
More about : RAB6A |
| Long gene name: |
RAB6A, member RAS oncogene family |
| Synonyms gene: |
RAB6 |
| Locus: |
11q13, 4 |
| Discovery year: |
1990-01-22 |
| GenBank acession: |
AF130986 |
| Entrez gene record: |
5870 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000134308 |