| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PAX6 |
| Specificity: |
Belongs to the paired homeobox family, PAX6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PAX6 |
| Gene ID: |
5080 |
| Swiss Prot: |
P26367 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Competes with PAX4 in binding to a common element in the glucagon, Isoform 5a appears to function as a molecular switch that specifies target genes, Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity), Required for the differentiation of pancreatic islet alpha cells (By similarity), central nervous system and pancreas, insulin and somatostatin promoters, nose, Transcription factor with important functions in the development of the eye |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
D11S812E AN WAGR |
| Also known as: |
PAX6 Polyclonal Antibody |
| Other name: |
Anti-PAX6 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PAX6 |
| Short name: |
Anti-PAX6 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PAX6 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8620 |
| Gene: |
PAX6 |
More about : PAX6 |
| Long gene name: |
paired box 6 |
| Synonyms gene: |
AN2 |
| Synonyms gene name: |
keratitis) , paired box gene 6 (aniridia |
| Synonyms name: |
aniridia, keratitis |
| Locus: |
11p13 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AY707088 |
| Entrez gene record: |
5080 |
| Pubmed identfication: |
1302030 |
| RefSeq identity: |
NM_001604 |
| Classification: |
PRD class homeoboxes and pseudogenes Paired boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000041447 |
| Locus Specific Databases: |
LOVD LRG_720 |