| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MYRF/C11orf9 |
| Specificity: |
This antibody reacts specifically with MYRF/C11orf9 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MYRF |
| Gene ID: |
745 |
| Swiss Prot: |
Q9Y2G1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage, MAG and PLP1 during oligodendrocyte (OL) maturation, MOG, Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, Myelin regulatory factor, Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832), N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression, thereby playing a central role in oligodendrocyte maturation and CNS myelination, viable oligodendrocyte phenotype (PubMed:23966832), Myelin regulatory factor: Consitutes a precursor of the transcription factor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Ndt80 pqn-47 MRF |
| Also known as: |
MYRF/C11orf9 Polyclonal Antibody |
| Other name: |
Anti-MYRF/C11orf9 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MYRF/C11orf9 |
| Short name: |
Anti-MYRF/C11orf9 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MYRF/C11orf9 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1181 |
| Gene: |
MYRF |
More about : MYRF |
| Long gene name: |
myelin regulatory factor |
| Synonyms gene: |
C11orf9 |
| Synonyms gene name: |
chromosome 11 open reading frame 9 |
| Synonyms name: |
myelin gene regulatory factor |
| Locus: |
11q12, 2 |
| Discovery year: |
1998-07-30 |
| Entrez gene record: |
745 |
| Pubmed identfication: |
10828591 12384578 |
| RefSeq identity: |
NM_013279 |
| Havana BLAST/BLAT: |
OTTHUMG00000168161 |