| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MAdCAM1 |
| Specificity: |
This antibody reacts specifically with MAdCAM1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MAdCAM1 |
| Gene ID: |
8174 |
| Swiss Prot: |
Q13477 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Isoform 2, It can bind both integrin alpha-4/beta-7 and L-selectin, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria, independent of L-selectin binding, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, regulating both the passage and retention of leukocytes, Cell adhesion leukocyte receptor expressed by mucosal venules |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MACAM1 |
| Also known as: |
MAdCAM1 Polyclonal Antibody |
| Other name: |
Anti-MAdCAM1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MAdCAM1 |
| Short name: |
Anti-MAdCAM1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-mucosal vascular addressin cellular adhesion molecule 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6765 |
| Gene: |
MADCAM1 |
More about : MADCAM1 |
| Long gene name: |
mucosal vascular addressin cell adhesion molecule 1 |
| Synonyms name: |
mucosal addressin cell adhesion molecule-1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2000-02-11 |
| GenBank acession: |
U43628 |
| Entrez gene record: |
8174 |
| Pubmed identfication: |
9162097 8609404 |
| RefSeq identity: |
NM_130760 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180548 |