| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NAP1L2 |
| Specificity: |
This antibody reacts specifically with NAP1L2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NAP1L2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In human and mouse there are 5 protein-coding genes which comprise the nucleosome assembly protein (NAP) family, NAP1L1 (NAP1) and NAP1L4 (NAP2) are ubiquitously expressed family members which have been the most extensively studied, NAP1L2, NAP1L2 (nucleosome assembly protein 1-like 2), NAP1L2 binds to chromatin and interacts with Histones H3 and H4, NAP1L3 and NAP1L5 are neuron-specific nucleosome assembly proteins translated from intronless genes which are monoallelically expressed, The function of NAP1L2 is not clearly defined although evidence suggests that NAP1L2 influences histone acetylation and therefore may play a significant role in regulating transcription in developing neurons, The remaining three family members, X-linked), also known as BPX (brain specific protein, is a 460 amino acid protein containing acidic domains which are thought to mediate histone interactions, Proper nucleosome assembly is critical for compacting DNA into chromatin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BPX MGC26243 |
| Also known as: |
NAP1L2 Polyclonal Antibody |
| Other name: |
Anti-NAP1L2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NAP1L2 |
| Short name: |
Anti-NAP1L2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NAP1L2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7638 |
| Gene: |
NAP1L2 |
More about : NAP1L2 |
| Long gene name: |
nucleosome assembly protein 1 like 2 |
| Synonyms gene name: |
nucleosome assembly protein 1-like 2 |
| Locus: |
Xq13, 2 |
| Discovery year: |
1996-09-03 |
| GenBank acession: |
AF136178 |
| Entrez gene record: |
4674 |
| Pubmed identfication: |
8789438 |
| RefSeq identity: |
NM_021963 |
| Havana BLAST/BLAT: |
OTTHUMG00000021827 |
| Locus Specific Databases: |
Mental Retardation database |