| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RASSF5 |
| Specificity: |
This antibody reacts specifically with RASSF5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RASSF5 |
| Gene ID: |
83593 |
| Swiss Prot: |
Q8WWW0 |
| Applications: |
IF(ICC), IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, May be involved in regulation of Ras apoptotic function, Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation, The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis, The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing, Together with RAP1A may participate in regulation of microtubule growth, resulting in an enhanced adhesion to ICAM1, Potential tumor suppressor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Maxp1 NORE1 RAPL |
| Also known as: |
RASSF5 Polyclonal Antibody |
| Other name: |
Anti-RASSF5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RASSF5 |
| Short name: |
Anti-RASSF5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RASSF5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17609 |
| Gene: |
RASSF5 |
More about : RASSF5 |
| Long gene name: |
Ras association domain family member 5 |
| Synonyms gene name: |
Ras association (RalGDS/AF-6) domain family member 5 |
| Synonyms name: |
novel Ras effector 1 regulator for cell adhesion and polarization enriched in lymphoid tissues |
| Locus: |
1q32, 1 |
| Discovery year: |
2003-04-02 |
| GenBank acession: |
BC004270 |
| Entrez gene record: |
83593 |
| Pubmed identfication: |
11978988 11965544 23972470 |
| RefSeq identity: |
NM_031437 |
| Classification: |
Ras association domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000184616 |