| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PCDH1 |
| Specificity: |
This antibody reacts specifically with PCDH1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PCDH1 |
| Gene ID: |
64121 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Involved in a variety of functions, Localized to cell-cell and cell-matrix boundaries and expressed at high levels in brain and neuro-glial cells, PCDH1 contains a C-terminal cytoplasmic region, PCDH1 is a 1, PCDH1 is thought to be involved in cell adhesion and cell-cell interactions and may play a role in neuronal development, a large group of related glycoproteins that mediate calcium-dependent cell-to-cell adhesion via a homophilic mechanism, an extracellular region and a transmembrane region, and is expressed as two isoforms due to alternative splicing events, protocadherins help to regulate neural development and synapse formation, 026 amino acid single-pass type I membrane protein that contains seven cadherin domains and is a member of the protocadherin family, Protocadherins are a subfamily of cadherins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
pc42 |
| Also known as: |
PCDH1 Polyclonal Antibody |
| Other name: |
Anti-PCDH1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PCDH1 |
| Short name: |
Anti-PCDH1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-protocadherin 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cell surfaces, PC42 and PCDH42, PCDH1 and IDBG-50917 and ENSG00000156453 and 5097, PCDH1 and IDBG-646122 and ENSBTAG00000012518 and 509388, Pcdh1 and IDBG-141384 and ENSMUSG00000051375 and 75599, protein binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007399 and nervous system development and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, protocadherin 1 |
| Identity: |
8655 |
| Gene: |
PCDH1 |
More about : PCDH1 |
| Long gene name: |
protocadherin 1 |
| Synonyms gene name: |
protocadherin 1 (cadherin-like 1) |
| Locus: |
5q31, 3 |
| Discovery year: |
1994-12-12 |
| GenBank acession: |
AK075233 |
| Entrez gene record: |
5097 |
| Pubmed identfication: |
8508762 |
| RefSeq identity: |
NM_032420 |
| Classification: |
Non-clustered protocadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000129661 |