| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PCDH17 |
| Specificity: |
This antibody reacts specifically with PCDH17 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PCDH17 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Expressed as multiple alternatively spliced isoforms, PCDH17 is a 1, PCDH17 is thought to function as a calcium-dependent cell adhesion protein that may play a role in establishing cell-cell connections within brain tissue, The gene encoding PCDH17 maps to human chromosome 13, There are three protocadherin gene clusters, all of which contain multiple tandemly arranged genes, and comprises nearly 4% of the human genome, beta and gamma, designated alpha, such as BRCA2 and RB1, which houses over 400 genes, 159 amino acid single-pass type I membrane protein that contains six cadherin domains, Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PCDH68 PCH68 |
| Also known as: |
PCDH17 Polyclonal Antibody |
| Other name: |
Anti-PCDH17 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PCDH17 |
| Short name: |
Anti-PCDH17 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-protocadherin 17 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
PCDH17 and IDBG-36343 and ENSG00000118946 and 27253, PCDH17 and IDBG-628612 and ENSBTAG00000010420 and 510554, Pcdh17 and IDBG-183216 and ENSMUSG00000035566 and 219228, Plasma membranes, protein binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, protocadherin 17 |
| Identity: |
14267 |
| Gene: |
PCDH17 |
More about : PCDH17 |
| Long gene name: |
protocadherin 17 |
| Locus: |
13q21, 1 |
| Discovery year: |
2000-12-19 |
| GenBank acession: |
AF029343 |
| Entrez gene record: |
27253 |
| Pubmed identfication: |
10835267 |
| RefSeq identity: |
NM_001040429 |
| Classification: |
Non-clustered protocadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000016992 |