| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Neurotrimin/HNT |
| Specificity: |
This antibody reacts specifically with Neurotrimin/HNT |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Neurotrimin/HNT |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Neurotrimin (hNT) is a neural cell adhesion molecule localizing to the cell membrane, Neurotrimin belongs to the IgLON family of proteins, Proper embryonic morphogenic development is also heavily dependent on the regulation of cell adhesion molecules, Regulation of neuronal synaptic adhesion by CAMs has proven important for learning and memory, The four major families of cell adhesion molecules are immunoglobulin (Ig) superfamily (calcium-independent transmembrane glycoproteins), a member of the larger immunoglobulin superfamily, calcium-dependent cadherins and divalent cation-dependent selectins, differentiation, embryogenesis, immune response and cancer metastasis by networking information from the extracellular matrix to the cell, integrins (transmembrane non-covalently linked heterodimers of Alpha and Beta subunits), where it acts as a lipid-anchor, Cell adhesion molecules (CAMs) influence cell growth |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HNT |
| Also known as: |
Neurotrimin/HNT Polyclonal Antibody |
| Other name: |
Anti-Neurotrimin/HNT Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Neurotrimin/HNT |
| Short name: |
Anti-Neurotrimin/HNT (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Neurotrimin/HNT (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
10449 |
| Gene: |
RREB1 |
More about : RREB1 |
| Long gene name: |
ras responsive element binding protein 1 |
| Synonyms name: |
hindsight homolog (drosophila) |
| Locus: |
6p24, 3 |
| Discovery year: |
1997-08-18 |
| GenBank acession: |
U26914 |
| Entrez gene record: |
6239 |
| Pubmed identfication: |
9367691 18394891 |
| Classification: |
Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000014201 |