| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CNTN4/AXCAM |
| Specificity: |
This antibody reacts specifically with CNTN4/AXCAM |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CNTN4/AXCAM |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
3PDS is a rare contiguous gene disorder involving the loss of the telomeric portion of the short arm of chromosome 3 and is characterized by developmental delay, Contactin 4 belongs to the immunoglobulin superfamily and is a member of the Contactin family, Contactin 4 contains four fibronectin type-3 domains, Contactin 4 is not believed to be expressed in skeletal muscle, Contactin 4 is primarily expressed in brain tissue, Defects in the CNTN4 gene are a cause of 3p deletion syndrome (3PDS), Highest expression has been found to be in the cerebellum, Isoform 2 is weakly expressed in cerebral cortex, Some expression is also found in testis, amygdala and spinal cord, and dysmorphic features, and has three isoforms (1, caudate nucleus, growth retardation, pancreas, six Ig-like C2-type domains, small intestine and kidney, thyroid, uterus, with lowest levels found in corpus callosum, 026 amino acid protein encoded by the human gene CNTN4, 2, 3), Contactin 4 is a 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BIG-2 |
| Also known as: |
CNTN4/AXCAM Polyclonal Antibody |
| Other name: |
Anti-CNTN4/AXCAM Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CNTN4/AXCAM |
| Short name: |
Anti-CNTN4/AXCAM (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-contactin 4/AXCAM (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CNTN4 and IDBG-13493 and ENSG00000144619 and 152330, CNTN4 and IDBG-644848 and ENSBTAG00000033225 and 521772, Cntn4 and IDBG-173779 and ENSMUSG00000064293 and 269784, Extracellular, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007158 and neuron cell-cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0007409 and axonogenesis and biological process this GO :0007411 and axon guidance and biological process this GO :0007413 and axonal fasciculation and biological process this GO :0007420 and brain development and biological process this GO :0030424 and axon and cellular component this GO :0031175 and neuron projection development and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0048167 and regulation of synaptic plasticity and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, contactin 4 |
| Identity: |
2174 |
| Gene: |
CNTN4 |
More about : CNTN4 |
| Long gene name: |
contactin 4 |
| Locus: |
3p26, 2 , 3-p26 |
| Discovery year: |
2000-05-26 |
| GenBank acession: |
AW665944 |
| Entrez gene record: |
152330 |
| Pubmed identfication: |
8586965 12202991 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000119031 |