| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CHL1/CALL |
| Specificity: |
This antibody reacts specifically with CHL1/CALL |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CHL1/CALL |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CHL1 is expressed in pyramidal neurons in a high-caudal to low-rostral gradient within the developing cortex, CHL1 plays a role in signal transduction pathways and is involved in cell migration, Close Homolog of L1 (CHL1), It is required for neuronal positioning and dendritic growth of pyramidal neurons in the posterior region of the developing mouse neocortex, also designated cell adhesion molecule with homology to L1CAM or L1 cell adhesion molecule 2, axon growth and guidance, belongs to the L1 gene family of neural cell adhesion molecules, Neural cell adhesion molecules play an important role in neural cell interactions and neuronal development and growth |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CALL L1CAM2 FLJ44930 MGC132578 |
| Also known as: |
CHL1/CALL Polyclonal Antibody |
| Other name: |
Anti-CHL1/CALL Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CHL1/CALL |
| Short name: |
Anti-CHL1/CALL (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-cell adhesion molecule including homology to L1CAM (close homolog on L1)/CALL (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CALL and L1CAM2, CHL1 and IDBG-13308 and ENSG00000134121 and 10752, CHL1 and IDBG-644887 and ENSBTAG00000002471 and 504415, Chl1 and IDBG-173444 and ENSMUSG00000030077 and 12661, Extracellular, protein binding, this GO :0001764 and neuron migration and biological process this GO :0002020 and protease binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0008344 and adult locomotory behavior and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030425 and dendrite and cellular component this GO :0031103 and axon regeneration and biological process this GO :0031175 and neuron projection development and biological process this GO :0035640 and exploration behavior and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045177 and apical part of cell and cellular component this GO :0050890 and cognition and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, cell adhesion molecule with homology to L1CAM (close homolog of L1) |
| Identity: |
1939 |
| Gene: |
CHL1 |
More about : CHL1 |
| Long gene name: |
cell adhesion molecule L1 like |
| Synonyms gene name: |
cell adhesion molecule with homology to L1CAM (close homologue of L1) cell adhesion molecule with homology to L1CAM (close homolog of L1) cell adhesion molecule L1-like |
| Synonyms name: |
neural cell adhesion molecule close homolog of L1 |
| Locus: |
3p26, 3 |
| Discovery year: |
1998-10-14 |
| GenBank acession: |
AF002246 |
| Entrez gene record: |
10752 |
| Pubmed identfication: |
9799093 |
| RefSeq identity: |
NM_006614 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000090601 |