| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BBC3 |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), WB |
| Recommended dilutions: |
1-0, 3ug/ml, ELISA (peptide) LOD: 1:16000, Western blot: 0 |
| Notes: |
This BBC3 antibody is specific for isoform 1, <, 1, Optimal dilution of the BBC3 antibody should be determined by the researcher, p> |
| Intented use: |
This BBC3 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
27113 |
| Purity: |
Antigen affinity |
| Description: |
Additional name(s) for this target protein: BCL2 binding component 3 |
| Immunogen: |
This sequence is specific to isoform 1/PUMA gamma, Amino acids DGGRPQRTVR were used as the immunogen for this BBC3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the BBC3 antibody at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BBC3 |
| Short name: |
BBC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
B-cell CLL/lymphoma 2 binding component 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BBC3 and IDBG-59341 and ENSG00000105327 and 100422832, Cytoplasm, protein binding, this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0008340 and determination of adult lifespan and biological process this GO :0032464 and positive regulation of protein homooli this GO merization and biological process this GO :0032471 and negative regulation of endoplasmic reticulum calcium ion concentration and biological process this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0045926 and negative regulation of growth and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0070059 and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process this GO :0070245 and positive regulation of thymocyte apoptotic process and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :0097194 and execution phase of apoptosis and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :2001056 and positive regulation of cysteine-type endopeptidase activity and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, 27113, 100422899, BCL2 binding component 3 |
| Identity: |
17868 |
| Gene: |
BBC3 |
More about : BBC3 |
| Long gene name: |
BCL2 binding component 3 |
| Synonyms: |
JFY1 PUMA |
| Locus: |
19q13, 32 |
| Discovery year: |
2002-07-22 |
| GenBank acession: |
AF332558 |
| Entrez gene record: |
27113 |
| Pubmed identfication: |
11463392 11572983 |
| RefSeq identity: |
NM_014417 |
| Classification: |
BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT: |
OTTHUMG00000183489 |