| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CRIPT |
| Specificity: |
This antibody reacts specifically with CRIPT |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CRIPT |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CRIPT (for cysteine-rich interactor of PDZ three), CRIPT induces the recruitment of PSD-95/SAP 90 to microtubules, CRIPT is widely expressed outside of the brain and is highly conserved from animals to plants suggesting a wider role in regulating cytoskeleton-membrane associations, These proteins are physically and functionally linked to cytoskeletal and/or signaling proteins, a novel postsynaptic protein, and it has been shown to bind directly to microtubules, are involved in the organization of synaptic structure, binds specifically to the PDZ3 domain of PSD-95/SAP 90, indicating that it may be responsible for cytoskeletal anchoring of PSD-95/SAP 90, which are known to bind to and cluster various membrane proteins, The PSD-95/SAP 90 family of proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HSPC139 |
| Also known as: |
CRIPT Polyclonal Antibody |
| Other name: |
Anti-CRIPT Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CRIPT |
| Short name: |
Anti-CRIPT (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CRIPT (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14312 |
| Gene: |
CRIPT |
More about : CRIPT |
| Long gene name: |
CXXC repeat containing interactor of PDZ3 domain |
| Synonyms gene name: |
cysteine-rich PDZ-binding protein |
| Locus: |
2p21 |
| Discovery year: |
2006-06-22 |
| GenBank acession: |
AA165108 |
| Entrez gene record: |
9419 |
| Pubmed identfication: |
16091592 11744724 10570482 9581762 |
| RefSeq identity: |
NM_014171 |
| Havana BLAST/BLAT: |
OTTHUMG00000128815 |