| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
Biotin |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ADRB3 |
| Specificity: |
This antibody reacts specifically with ADRB3 Biotin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ADRB3 |
| Gene ID: |
155 |
| Swiss Prot: |
P13945 |
| Applications: |
IHC-P |
| Applications with corresponding dilutions: |
IHC-P(1:100-500) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Beta-3 is involved in the regulation of lipolysis and thermogenesis, Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Also known as: |
ADRB3 Polyclonal Antibody Biotin |
| Other name: |
Anti-ADRB3 Polyclonal Biotin |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase |
| Conjugation: |
Biotinylated |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ADRB3 |
| Short name: |
Anti-ADRB3 (Polyclonal) |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
Biotin |
| Alternative name: |
biotinilated, antibody to-adrenoceptor b 3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ADRB3 and IDBG-17239 and ENSG00000188778 and 155, ADRB3 and IDBG-629092 and ENSBTAG00000017981 and 281606, Adrb3 and IDBG-145892 and ENSMUSG00000031489 and 11556, BETA3AR, coupled to cyclic nucleotide second messenger and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0007568 and aging and biological process this GO :0009409 and response to cold and biological process this GO :0015052 and beta3-adrenergic receptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0031649 and heat generation and biological process this GO :0031699 and beta-3 adrenergic receptor binding and molecular function this GO :0040015 and negative regulation of multicellular organism growth and biological process this GO :0042755 and eating behavior and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0046677 and response to antibiotic and biological process this GO :0050873 and brown fat cell differentiation and biological process this GO :0051379 and epinephrine binding and molecular function this GO :0051380 and norepinephrine binding and molecular function this GO :0071875 and adrenergic receptor signaling pathway and biological process, norepinephrine binding, nuclei, this GO :0002024 and diet induced thermogenesis and biological process this GO :0002025 and vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004939 and beta-adrenergic receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006091 and generation of precursor metabolites and energy and biological process this GO :0006112 and energy reserve metabolic process and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007187 and G-protein coupled receptor signaling pathway, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004939 : beta-adrenergic receptor activity and also this GO :0005515 : protein binding and also this GO :0015052 : beta3-adrenergic receptor activity and also this GO :0031699 : beta-3 adrenergic receptor binding and also this GO :0042803 : protein homodimerization activity and also this GO :0051379 : epinephrine binding and also this GO :0051380 : norepinephrine binding, this GO :0004939 : beta-adrenergic receptor activity, this GO :0005515 : protein binding, this GO :0015052 : beta3-adrenergic receptor activity, this GO :0031699 : beta-3 adrenergic receptor binding, this GO :0042803 : protein homodimerization activity, this GO :0051379 : epinephrine binding, this GO :0051380 : norepinephrine binding, adrenoceptor beta 3 |
| Identity: |
288 |
| Gene: |
ADRB3 |
More about : ADRB3 |
| Long gene name: |
adrenoceptor beta 3 |
| Synonyms gene name: |
adrenergic, beta-3-, receptor |
| Locus: |
8p11, 23 |
| Discovery year: |
1993-10-04 |
| GenBank acession: |
AY487247 |
| Entrez gene record: |
155 |
| Pubmed identfication: |
7898940 15123695 |
| RefSeq identity: |
NM_000025 |
| Classification: |
Adrenoceptors |
| Havana BLAST/BLAT: |
OTTHUMG00000164028 |