| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
Biotin |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Uroplakin 1A |
| Specificity: |
This antibody reacts specifically with Uroplakin 1A Biotin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Helical, Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Uroplakin 1A |
| Gene ID: |
11045 |
| Applications: |
WB |
| Applications with corresponding dilutions: |
WB(1:100-1000) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
May play an important role in normal bladder epithelial physiology, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions, Component of the asymmetric unit membrane (AUM) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Synonyms: |
TSPAN21 |
| Also known as: |
Uroplakin 1A Polyclonal Antibody Biotin |
| Other name: |
Anti-Uroplakin 1A Polyclonal Biotin |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase |
| Conjugation: |
Biotinylated |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Uroplakin 1A |
| Short name: |
Anti-Uroplakin 1A (Polyclonal) |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
Biotin |
| Alternative name: |
biotinilated, antibody to-Uroplakin 1A (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
12577 |
| Gene: |
UPK1A |
More about : UPK1A |
| Long gene name: |
uroplakin 1A |
| Locus: |
19q13, 12 |
| Discovery year: |
1999-08-26 |
| GenBank acession: |
AF085807 |
| Entrez gene record: |
11045 |
| Pubmed identfication: |
9846985 10404304 |
| Classification: |
Tetraspanins |
| Havana BLAST/BLAT: |
OTTHUMG00000048115 |