| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NME1 |
| Specificity: |
This antibody reacts specifically with NME1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Nm23-H1 |
| Gene ID: |
4830 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
G protein-coupled receptor endocytosis, Has tumor metastasis-suppressive capacity, Involved in cell proliferation, Possesses nucleoside-diphosphate kinase, Required for neural development including neural patterning and cell fate determination, and gene expression, differentiation and development, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities, serine/threonine-specific protein kinase, signal transduction, NM23A plays a major role in the synthesis of nucleoside triphosphates other than ATP |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NM23 NM23-H1 NDPKA |
| Also known as: |
NME1 Polyclonal Antibody |
| Other name: |
Anti-NME1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NME1 |
| Short name: |
Anti-NME1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NME/NM23 nucleoside diphosphate kinase 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AWD and GAAD and NB and NBS and NDKA and NDPK-A and NDPKA and NM23 and NM23-H1, NME1 and IDBG-409263 and ENSG00000239672 and 4830, NME1 and IDBG-638442 and ENSBTAG00000004651 and 404189, Nme1 and IDBG-208565 and ENSMUSG00000037601 and 18102, nuclei, poly(A) RNA binding, this GO :0000287 and magnesium ion binding and molecular function this GO :0004536 and deoxyribonuclease activity and molecular function this GO :0004550 and nucleoside diphosphate kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006165 and nucleoside diphosphate phosphorylation and biological process this GO :0006183 and GTP biosynthetic process and biological process this GO :0006228 and UTP biosynthetic process and biological process this GO :0006241 and CTP biosynthetic process and biological process this GO :0006308 and DNA catabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0015949 and nucleobase-containing small molecule interconversion and biological process this GO :0016020 and membrane and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043024 and ribosomal small subunit binding and molecular function this GO :0043388 and positive regulation of DNA binding and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0055086 and nucleobase-containing small molecule metabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004536 : deoxyribonuclease activity and also this GO :0004550 : nucleoside diphosphate kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005525 : GTP binding and also this GO :0042802 : identical protein binding and also this GO :0043024 : ribosomal small subunit binding and also this GO :0044822 : poly(A) RNA binding, this GO :0004536 : deoxyribonuclease activity, this GO :0004550 : nucleoside diphosphate kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005525 : GTP binding, this GO :0042802 : identical protein binding, this GO :0043024 : ribosomal small subunit binding, this GO :0044822 : poly(A) RNA binding, NME/NM23 nucleoside diphosphate kinase 1 |
| Identity: |
7849 |
| Gene: |
NME1 |
More about : NME1 |
| Long gene name: |
NME/NM23 nucleoside diphosphate kinase 1 |
| Synonyms gene name: |
non-metastatic cells 1, protein (NM23A) expressed in |
| Locus: |
17q21, 33 |
| Discovery year: |
1991-07-26 |
| GenBank acession: |
AL360191 X17620 |
| Entrez gene record: |
4830 |
| Pubmed identfication: |
8270257 19852809 |
| RefSeq identity: |
NM_000269 |
| Classification: |
NME/NM23 family |
| Havana BLAST/BLAT: |
OTTHUMG00000137474 |