| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Collagen alpha-1(II) chain |
| Specificity: |
This antibody reacts specifically with COL2A1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Collagen alpha-1(II) chain |
| Gene ID: |
1280 |
| Swiss Prot: |
P02458 |
| Applications: |
IF(ICC) |
| Applications with corresponding dilutions: |
IF(ICC)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces, Type II collagen is specific for cartilaginous tissues |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
STL1 |
| Also known as: |
COL2A1 Polyclonal Antibody |
| Other name: |
Anti-COL2A1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
COL2A1 |
| Short name: |
Anti-COL2A1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, a 1 (polyclonal) , classification II, antibody to-collagen |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ANFH and AOM and COL11A3 and SEDC and STL1, COL2A1 and IDBG-29355 and ENSG00000139219 and 1280, COL2A1 and IDBG-632928 and ENSBTAG00000013155 and 407142, Col2a1 and IDBG-179337 and ENSMUSG00000022483 and 12824, Extracellular, alpha 1, platelet-derived growth factor binding, this GO :0001501 and skeletal system development and biological process this GO :0001502 and cartilage condensation and biological process this GO :0001503 and ossification and biological process this GO :0001894 and tissue homeostasis and biological process this GO :0001958 and endochondral ossification and biological process this GO :0002062 and chondrocyte differentiation and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005585 and collagen type II and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0006029 and proteoglycan metabolic process and biological process this GO :0007411 and axon guidance and biological process this GO :0007417 and central nervous system development and biological process this GO :0007601 and visual perception and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030020 and extracellular matrix structural constituent conferring tensile strength and molecular function this GO :0030198 and extracellular matrix organization and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0030903 and notochord development and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0035108 and limb morphogenesis and biological process this GO :0042472 and inner ear morphogenesis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048407 and platelet-derived growth factor binding and molecular function this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048839 and inner ear development and biological process this GO :0051216 and cartilage development and biological process this GO :0060021 and palate development and biological process this GO :0060174 and limb bud formation and biological process this GO :0060272 and embryonic skeletal joint morphogenesis and biological process this GO :0060348 and bone development and biological process this GO :0060351 and cartilage development involved in endochondral bone morphogenesis and biological process this GO :0071599 and otic vesicle development and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005201 : extracellular matrix structural constituent, this GO :0005201 : extracellular matrix structural constituent and also this GO :0005515 : protein binding and also this GO :0030020 : extracellular matrix structural constituent conferring tensile strength and also this GO :0042802 : identical protein binding and also this GO :0046872 : metal ion binding and also this GO :0048407 : platelet-derived growth factor binding, this GO :0005515 : protein binding, this GO :0030020 : extracellular matrix structural constituent conferring tensile strength, this GO :0042802 : identical protein binding, this GO :0046872 : metal ion binding, this GO :0048407 : platelet-derived growth factor binding, type II, collagen |
| Identity: |
2200 |
| Gene: |
COL2A1 |
More about : COL2A1 |
| Long gene name: |
collagen type II alpha 1 chain |
| Synonyms gene: |
SEDC AOM |
| Synonyms gene name: |
alpha 1 (primary osteoarthritis, alpha 1 collagen type II alpha 1 , collagen, congenital) arthroophthalmopathy, progressive (Stickler syndrome) collagen, spondyloepiphyseal dysplasia, type II, type II |
| Locus: |
12q13, 11 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X16468 |
| Entrez gene record: |
1280 |
| Pubmed identfication: |
1677770 |
| RefSeq identity: |
NM_001844 |
| Classification: |
Collagens |
| Havana BLAST/BLAT: |
OTTHUMG00000149896 |
| Locus Specific Databases: |
Belgium , Ghent, LOVD - Center for Medical Genetics |