| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Nemo-like kinase Thr298 |
| Specificity: |
This antibody reacts specifically with Nemo-like kinase (Thr298) |
| Modification: |
Phosphorylation |
| Modification site: |
Thr298 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human Nemo-like kinase around the phosphorylation site of Thr298 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
(referenced from swissprot), CREBBP, It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor, It may suppress a wide range of transcription factors by phosphorylation of the coactivator, Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DKFZp761G1211, FLJ21033, LAK1, NLK_HUMAN, Nemo like kinase, Nemo-like kinase, Nemo-like kinase T298, Nlk, Protein LAK1, Serine/threonine protein kinase NLK, Serine/threonine-protein kinase NLK, p-Nemo-like kinase T298, p-Nemo-like kinase Thr298, Nemo-like kinase Thr298 |
| Also known as: |
Nemo-like kinase (Thr298) Antibody |
| Other name: |
Anti-Nemo-like kinase (Thr298) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Nemo-like kinase (Thr298) |
| Short name: |
Anti-Nemo-like kinase (Thr298) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Nemo-like phosphorylation catalyst (Thr298) |