| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Factor VIIIa light chain |
| Specificity: |
This antibody reacts specifically with Factor VIIIa light chain |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Factor VIIIa light chain |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in this gene results in hemophilia A, Jul 2008], This binding domain is essential for coagulant activity, This gene produces two alternatively spliced transcripts, This protein undergoes multiple cleavage events, Transcript variant 1 encodes a large glycoprotein, Transcript variant 2 encodes a putative small protein, [provided by RefSeq, a common recessive X-linked coagulation disorder, converts factor X to the activated form Xa, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, isoform a, isoform b, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex, which consists primarily of the phospholipid binding domain of factor VIIIc, which participates in the intrinsic pathway of blood coagulation, This gene encodes coagulation factor VIII |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AHF, Ahf, Antihemophilic factor, Coagulation factor VIII, Coagulation factor VIII associated protein b, Coagulation factor VIII isoform b, Coagulation factor VIII procoagulent component, Coagulation factor VIIIc, DXS1253E, Dna segment on chromosome x unique 1253 expressed sequence, Dxs1253e, F8, F8 protein, F8B, F8C, F8b, F8c, FA8_HUMAN, FVIII, FVIII, FactorVIII, HEMA, Hema, Hema coagulation factor VIIIc procoagulent component, Hemophilia a, Hemophilia classic, OTTHUMP00000061446, Procoagulant component, coagulation factor VIII |
| Also known as: |
Factor VIIIa light chain Antibody |
| Other name: |
Anti-Factor VIIIa light chain |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Factor VIIIa light chain |
| Short name: |
Fluor 594, Anti-Factor VIIIa light chain |
| Technique: |
light |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Factor VIIIa light epitope |