| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
c-ABL Thr394 |
| Specificity: |
This antibody reacts specifically with c-ABL(Thr394) |
| Modification: |
Phosphorylation |
| Modification site: |
Thr394 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Thr394 |
| Gene ID: |
25 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase, the c Abl proto oncogene undergoes a (9, 22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22, The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ABL |
| Also known as: |
c-ABL(Thr394) Polyclonal Antibody |
| Other name: |
Anti-c-ABL(Thr394) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
c-ABL(Thr394) |
| Short name: |
Anti-c-ABL(Thr394) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-c-ABL(Thr394) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7467 |
| Gene: |
MTTP |
More about : MTTP |
| Long gene name: |
microsomal triglyceride transfer protein |
| Synonyms gene: |
MTP |
| Synonyms gene name: |
88kD) microsomal triglyceride transfer protein (large polypeptide, 88kDa) , microsomal triglyceride transfer protein (large polypeptide |
| Locus: |
4q23 |
| Discovery year: |
1994-12-07 |
| Entrez gene record: |
4547 |
| Pubmed identfication: |
8111381 |
| Havana BLAST/BLAT: |
OTTHUMG00000131023 |