| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MCM7/CDC47 |
| Specificity: |
This antibody reacts specifically with MCM7/CDC47 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CDC47 |
| Gene ID: |
4176 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
4 and 6 proteins possesses DNA helicase activity, Alternatively spliced transcript variants encoding distinct isoforms have been reported, CDK4, Cyclin D1-dependent kinase, Jul 2008], The MCM complex consisting of this protein and MCM2, The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins, [provided by RefSeq, and may act as a DNA unwinding enzyme, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB, is found to associate with this protein, The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CDC47 PPP1R104 |
| Also known as: |
MCM7/CDC47 Polyclonal Antibody |
| Other name: |
Anti-MCM7/CDC47 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MCM7/CDC47 |
| Short name: |
Anti-MCM7/CDC47 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MCM7/CDC47 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6950 |
| Gene: |
MCM7 |
More about : MCM7 |
| Long gene name: |
minichromosome maintenance complex component 7 |
| Synonyms gene: |
MCM2 |
| Synonyms gene name: |
cerevisiae) , cerevisiae) 7 MCM7 minichromosome maintenance deficient 7 (S, minichromosome maintenance deficient (S |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 104 |
| Locus: |
7q22, 1 |
| Discovery year: |
1994-12-13 |
| Entrez gene record: |
4176 |
| Pubmed identfication: |
7842741 |
| Classification: |
Protein phosphatase 1 regulatory subunits MCM family |
| Havana BLAST/BLAT: |
OTTHUMG00000154671 |