| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CHI3L1 |
| Specificity: |
This antibody reacts specifically with CHI3L1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from Human CHI3L1 |
| Gene ID: |
1116 |
| Swiss Prot: |
P36222 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also regulates hyperoxia-induced injury, Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs, Has no chitinase activity, May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment, Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells, Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance, dendritic cell accumulation and M2 macrophage differentiation, inflammation and epithelial apoptosis in lung, inflammatory cell apoptosis, regulating allergen sensitization, Carbohydrate-binding lectin with a preference for chitin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GP39 YKL40 |
| Also known as: |
CHI3L1 Polyclonal Antibody |
| Other name: |
Anti-CHI3L1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CHI3L1 |
| Short name: |
Anti-CHI3L1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CHI3L1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1932 |
| Gene: |
CHI3L1 |
More about : CHI3L1 |
| Long gene name: |
chitinase 3 like 1 |
| Synonyms gene name: |
chitinase 3-like 1 (cartilage glycoprotein-39) |
| Synonyms name: |
cartilage glycoprotein-39 |
| Locus: |
1q32, 1 |
| Discovery year: |
1994-12-20 |
| GenBank acession: |
BC008568 |
| Entrez gene record: |
1116 |
| Pubmed identfication: |
8245017 9244440 |
| RefSeq identity: |
NM_001276 |
| Classification: |
Chitinases |
| Havana BLAST/BLAT: |
OTTHUMG00000042122 |