| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
KRT14), Cytokeratin 14 (CK14 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, Immunohistochemistry (FFPE): 1-2ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the Cytokeratin 14 antibody should be determined by the researcher |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P02533 |
| Purity: |
Antigen affinity |
| Description: |
At least one pseudogene has been identified at 17p12-p11, In humans it is encoded by the KRT14 gene, Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex, This gene product, a type I keratin, a type II keratin, also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14), is a member of the type I keratin family of intermediate filament proteins, is usually found as a heterotetramer with two keratin 5 molecules, Cytokeratin 14 |
| Immunogen: |
Amino acids 446-472 (RQIRTKVMDVHDGKVVSTHEQVLRTKN-human) were used as the immunogen for the Cytokeratin 14 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cytokeratin 14 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
nuclear, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
KRT14), Cytokeratin 14 (CK14 |
| Short name: |
KRT14), Cytokeratin 14 Antibody (CK14 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
KRT14), Cytokeratin 14 (Antibody to) (CK14 |
| Alternative technique: |
antibodies |
| Identity: |
6416 |
| Gene: |
KRT14 |
More about : KRT14 |
| Long gene name: |
keratin 14 |
| Synonyms gene: |
EBS3 EBS4 |
| Synonyms gene name: |
Dowling-Meara, Koebner) keratin 14, keratin 14 (epidermolysis bullosa simplex, type I |
| Synonyms name: |
Dowling-Meara, Koebner , epidermolysis bullosa simplex |
| Locus: |
17q21, 2 |
| Discovery year: |
1992-04-09 |
| GenBank acession: |
BC002690 |
| Entrez gene record: |
3861 |
| Pubmed identfication: |
1717157 16831889 |
| RefSeq identity: |
NM_000526 |
| Classification: |
Keratins, type I |
| Havana BLAST/BLAT: |
OTTHUMG00000133426 |