| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Fibrinogen gamma chain (FGG) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, Immunohistochemistry (FFPE): 1-2ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the Fibrinogen gamma chain antibody should be determined by the researcher |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P02679 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in transcript variants encoding different isoforms, Following vascular injury, In addition, Mutations in this gene lead to several disorders, The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains, also known as FGG, and are mitogens for several cell types, display vasoconstrictor and chemotactic activities, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots, hypofibrinogenemia and thrombophilia, including dysfibrinogenemia, is a human gene found on chromosome 4, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, Fibrinogen gamma chain |
| Immunogen: |
Amino acids 133-163 (IRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE-human) were used as the immunogen for the Fibrinogen gamma chain antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Fibrinogen gamma chain antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Secreted |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Fibrinogen gamma chain (FGG) |
| Short name: |
Fibrinogen gamma chain Antibody (FGG) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Fibrinogen g epitope (Antibody to) (fibrinogen gamma chain) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, FGG and IDBG-42165 and ENSG00000171557 and 2266, FGG and IDBG-628944 and ENSBTAG00000006745 and 280792, Fgg and IDBG-154510 and ENSMUSG00000033860 and 99571, bridging, bridging and also this GO :0046872 : metal ion binding and also this GO :0050839 : cell adhesion molecule binding, bridging and molecular function this GO :0031091 and platelet alpha granule and cellular component this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0034116 and positive regulation of heterotypic cell-cell adhesion and biological process this GO :0043623 and cellular protein complex assembly and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045921 and positive regulation of exocytosis and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050714 and positive regulation of protein secretion and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051258 and protein polymerization and biological process this GO :0051592 and response to calcium ion and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070527 and platelet aggregation and biological process this GO :0072562 and blood microparticle and cellular component this GO :0090277 and positive regulation of peptide hormone secretion and biological process this GO :1900026 and positive regulation of substrate adhesion-dependent cell spreading and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, protein binding, this GO :0002576 and platelet degranulation and biological process this GO :0005102 and receptor binding and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005577 and fibrinogen complex and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030674 and protein binding, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005198 : structural molecule activity and also this GO :0030674 : protein binding, this GO :0005198 : structural molecule activity, this GO :0030674 : protein binding, this GO :0046872 : metal ion binding, this GO :0050839 : cell adhesion molecule binding, fibrinogen gamma chain |
| Identity: |
3694 |
| Gene: |
FGG |
More about : FGG |
| Long gene name: |
fibrinogen gamma chain |
| Synonyms gene name: |
fibrinogen, gamma polypeptide |
| Locus: |
4q32, 1 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2266 |
| RefSeq identity: |
NM_021870 |
| Classification: |
Endogenous ligands Fibrinogen C domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150329 |
| Locus Specific Databases: |
A Database For Human Fibrinogen Variants LRG_585 |