| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CYP17A1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, Immunohistochemistry (FFPE): 1-2ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the CYP17A1 antibody should be determined by the researcher |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P05093 |
| Purity: |
Antigen affinity |
| Description: |
17-alpha-hydroxylase/17, It has both 17alpha-hydroxylase and 17, Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, This gene encodes a member of the cytochrome P450 superfamily of enzymes, This protein localizes to the endoplasmic reticulum, also called steroid 17<, and adrenal hyperplasia, and estrogens, androgens, glucocorticoids, is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10, mineralocorticoids, pseudohermaphroditism, steroids and other lipids, -monooxygenase, /font>, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, 20-lyase deficiency, Cytochrome P450 17A1, a<, font face=symbol> |
| Immunogen: |
Amino acids 383-419 (EFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLN-human) were used as the immunogen for the CYP17A1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CYP17A1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
membranous, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CYP17A1 |
| Short name: |
CYP17A1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CYP17A1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2593 |
| Gene: |
CYP17A1 |
More about : CYP17A1 |
| Long gene name: |
cytochrome P450 family 17 subfamily A member 1 |
| Synonyms gene: |
CYP17 |
| Synonyms gene name: |
adrenal hyperplasia cytochrome P450, cytochrome P450, family 17, polypeptide 1 , subfamily A, subfamily XVII (steroid 17-alpha-hydroxylase) |
| Synonyms: |
P450C17 CPT7 S17AH |
| Synonyms name: |
Steroid 17-alpha-monooxygenase |
| Locus: |
10q24, 32 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M19489 |
| Entrez gene record: |
1586 |
| Pubmed identfication: |
1347802 9888582 |
| RefSeq identity: |
NM_000102 |
| Classification: |
Cytochrome P450 family 17 |
| Havana BLAST/BLAT: |
OTTHUMG00000018969 |