| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MMP13 / Collagenase 3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the MMP13 antibody should be determined by the researcher |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This MMP13 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P45452 |
| Purity: |
Antigen affinity |
| Description: |
It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis, Mutations in this gene are associated with metaphyseal anadysplasia, Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, The encoded preproprotein is proteolytically processed to generate the mature protease, This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs), This gene is part of a cluster of MMP genes on chromosome 11, This protease cleaves type II collagen more efficiently than types I and III, and tissue remodeling, as well as in disease processes, reproduction, such as arthritis and metastasis, such as embryonic development, Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene |
| Immunogen: |
Amino acids 109-154 (RTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFT-human) were used as the immunogen for the MMP13 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MMP13 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
extracellular matrix, Secreted |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MMP13 / Collagenase 3 |
| Short name: |
MMP13 Antibody / Collagenase 3 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MMP13 (Antibody to) / Collagenase 3 |
| Alternative technique: |
antibodies |
| Identity: |
7159 |
| Gene: |
MMP13 |
More about : MMP13 |
| Long gene name: |
matrix metallopeptidase 13 |
| Synonyms gene name: |
matrix metalloproteinase 13 (collagenase 3) |
| Synonyms: |
CLG3 |
| Synonyms name: |
collagenase 3 |
| Locus: |
11q22, 2 |
| Discovery year: |
1994-11-20 |
| GenBank acession: |
X75308 |
| Entrez gene record: |
4322 |
| Pubmed identfication: |
8207000 |
| RefSeq identity: |
NM_002427 |
| Classification: |
Endogenous ligands Matrix metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000165850 |