| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DRD2 |
| Specificity: |
This antibody reacts specifically with DRD2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DRD2 |
| Gene ID: |
1813 |
| Swiss Prot: |
P14416 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
DRD2 Polyclonal Antibody |
| Other name: |
Anti-DRD2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DRD2 |
| Short name: |
Anti-DRD2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-dopamine receptor D2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
D2DR and D2R, DRD2 and IDBG-630610 and ENSBTAG00000010860 and 281126, DRD2 and IDBG-71698 and ENSG00000149295 and 1813, Drd2 and IDBG-162803 and ENSMUSG00000032259 and 13489, GABAergic and biological process this GO :0032467 and positive regulation of cytokinesis and biological process this GO :0032922 and circadian regulation of gene expression and biological process this GO :0033602 and negative regulation of dopamine secretion and biological process this GO :0034776 and response to histamine and biological process this GO :0035094 and response to nicotine and biological process this GO :0035240 and dopamine binding and molecular function this GO :0035255 and ionotropic glutamate receptor binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0035810 and positive regulation of urine volume and biological process this GO :0035815 and positive regulation of renal sodium excretion and biological process this GO :0036126 and sperm flagellum and cellular component this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042220 and response to cocaine and biological process this GO :0042321 and negative regulation of circadian sleep/wake cycle, Plasma membranes, coupled via Gi/ this GO , coupled via Gi/ this GO and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004952 : dopamine receptor activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0035240 : dopamine binding and also this GO :0035255 : ionotropic glutamate receptor binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity, coupled via Gi/ this GO and molecular function this GO :0001659 and temperature homeostasis and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001669 and acrosomal vesicle and cellular component this GO :0001963 and synaptic transmission, dopamine neurotransmitter receptor activity, dopaminergic and biological process this GO :0001964 and startle response and biological process this GO :0001975 and response to amphetamine and biological process this GO :0001976 and neurological system process involved in regulation of systemic arterial blood pressure and biological process this GO :0002027 and regulation of heart rate and biological process this GO :0002028 and regulation of sodium ion transport and biological process this GO :0002031 and G-protein coupled receptor internalization and biological process this GO :0002052 and positive regulation of neuroblast proliferation and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004952 and dopamine receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007194 and negative regulation of adenylate cyclase activity and biological process this GO :0007195 and adenylate cyclase-inhibiting dopamine receptor signaling pathway and biological process this GO :0007212 and dopamine receptor signaling pathway and biological process this GO :0007270 and neuron-neuron synaptic transmission and biological process this GO :0007409 and axonogenesis and biological process this GO :0007416 and synapse assembly and biological process this GO :0007608 and sensory perception of smell and biological process this GO :0007616 and long-term memory and biological process this GO :0007625 and grooming behavior and biological process this GO :0007626 and locomotory behavior and biological process this GO :0007628 and adult walking behavior and biological process this GO :0007631 and feeding behavior and biological process this GO :0008104 and protein localization and biological process this GO :0008144 and drug binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008306 and associative learning and biological process this GO :0008542 and visual learning and biological process this GO :0009416 and response to light stimulus and biological process this GO :0009636 and response to toxic substance and biological process this GO :0010039 and response to iron ion and biological process this GO :0014059 and regulation of dopamine secretion and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0014854 and response to inactivity and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0021756 and striatum development and biological process this GO :0021769 and orbitofrontal cortex development and biological process this GO :0021853 and cerebral cortex GABAergic interneuron migration and biological process this GO :0021984 and adenohypophysis development and biological process this GO :0030139 and endocytic vesicle and cellular component this GO :0030336 and negative regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030432 and peristalsis and biological process this GO :0030534 and adult behavior and biological process this GO :0030672 and synaptic vesicle membrane and cellular component this GO :0030814 and regulation of cAMP metabolic process and biological process this GO :0030900 and forebrain development and biological process this GO :0031223 and auditory behavior and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032147 and activation of protein kinase activity and biological process this GO :0032228 and regulation of synaptic transmission, glutamatergic and biological process this GO :0060124 and positive regulation of growth hormone secretion and biological process this GO :0060134 and prepulse inhibition and biological process this GO :0060158 and phospholipase C-activating dopamine receptor signaling pathway and biological process this GO :0060160 and negative regulation of dopamine receptor signaling pathway and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0090325 and regulation of locomotion involved in locomotory behavior and biological process this GO :1900273 and positive regulation of long-term synaptic potentiation and biological process this GO :1901386 and negative regulation of voltage-gated calcium channel activity and biological process, sleep and biological process this GO :0042417 and dopamine metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043197 and dendritic spine and cellular component this GO :0043204 and perikaryon and cellular component this GO :0043266 and regulation of potassium ion transport and biological process this GO :0043278 and response to morphine and biological process this GO :0043408 and regulation of MAPK cascade and biological process this GO :0043473 and pigmentation and biological process this GO :0043666 and regulation of phosphoprotein phosphatase activity and biological process this GO :0043679 and axon terminus and cellular component this GO :0045471 and response to ethanol and biological process this GO :0045745 and positive regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0045776 and negative regulation of blood pressure and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046488 and phosphatidylinositol metabolic process and biological process this GO :0046676 and negative regulation of insulin secretion and biological process this GO :0046717 and acid secretion and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048148 and behavioral response to cocaine and biological process this GO :0048149 and behavioral response to ethanol and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048678 and response to axon injury and biological process this GO :0048755 and branching morphogenesis of a nerve and biological process this GO :0050482 and arachidonic acid secretion and biological process this GO :0050709 and negative regulation of protein secretion and biological process this GO :0050804 and regulation of synaptic transmission and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051481 and negative regulation of cytosolic calcium ion concentration and biological process this GO :0051482 and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway and biological process this GO :0051584 and regulation of dopamine uptake involved in synaptic transmission and biological process this GO :0051586 and positive regulation of dopamine uptake involved in synaptic transmission and biological process this GO :0051823 and regulation of synapse structural plasticity and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0051967 and negative regulation of synaptic transmission, this GO :0001591 and dopamine neurotransmitter receptor activity, this GO :0001591 : dopamine neurotransmitter receptor activity, this GO :0001591 : dopamine neurotransmitter receptor activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0004952 : dopamine receptor activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0015459 : potassium channel regulator activity, this GO :0035240 : dopamine binding, this GO :0035255 : ionotropic glutamate receptor binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, dopamine receptor D2 |
| Identity: |
3023 |
| Gene: |
DRD2 |
More about : DRD2 |
| Long gene name: |
dopamine receptor D2 |
| Locus: |
11q23, 2 |
| Discovery year: |
1989-02-23 |
| GenBank acession: |
M29066 |
| Entrez gene record: |
1813 |
| RefSeq identity: |
NM_000795 |
| Classification: |
Dopamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000167717 |