| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LIGHTR / TNFRSF14 / HVEM |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (protein), WB |
| Recommended dilutions: |
request BSA-free format for coating, 5-1ug/ml, 5-1ug/ml (human protein tested), ELISA: 0, Western blot: 0 |
| Added buffer: |
025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use: |
This HVEM antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q92956 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcript variants, It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response, also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily, mediating its entry into cells, Herpesvirus entry mediator (HVEM) |
| Immunogen: |
Amino acids L39-V202 from the human protein were used as the immunogen for the HVEM antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HVEM antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LIGHTR / TNFRSF14 / HVEM |
| Short name: |
LIGHTR Antibody / TNFRSF14 / HVEM |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 14 / HVEM, LIGHTR (Antibody to) / tumor necrosis factor receptor superfamily |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATAR and CD270 and HVEA and HVEM and LIGHTR and TR2, Cell surfaces, TNFRSF14 and IDBG-86399 and ENSG00000157873 and 8764, Tnfrsf14 and IDBG-207237 and ENSMUSG00000042333 and 230979, member 14, this GO :0001618 and virus receptor activity and molecular function this GO :0002741 and positive regulation of cytokine secretion involved in immune response and biological process this GO :0005031 and tumor necrosis factor-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0046642 and negative regulation of alpha-beta T cell proliferation and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :2000406 and positive regulation of T cell migration and biological process, this GO :0001618 : virus receptor activity, this GO :0001618 : virus receptor activity and also this GO :0005031 : tumor necrosis factor-activated receptor activity and also this GO :0005515 : protein binding and also this GO :0031625 : ubiquitin protein ligase binding, this GO :0005031 : tumor necrosis factor-activated receptor activity, this GO :0005515 : protein binding, this GO :0031625 : ubiquitin protein ligase binding, ubiquitin protein ligase binding, tumor necrosis factor receptor superfamily |
| Identity: |
11912 |
| Gene: |
TNFRSF14 |
More about : TNFRSF14 |
| Long gene name: |
TNF receptor superfamily member 14 |
| Synonyms gene name: |
member 14 , member 14 (herpesvirus entry mediator) tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily |
| Synonyms: |
HVEM ATAR TR2 LIGHTR HVEA CD270 |
| Synonyms name: |
herpesvirus entry mediator |
| Locus: |
1p36, 32 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
U70321 |
| Entrez gene record: |
8764 |
| Pubmed identfication: |
8898196 9162061 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000000792 |